USB-AIO16-64MA-OEM Multifunction 64-Channel Economy Analog I/O USB Family

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  • High-speed USB 2.0 multifunction DAQ, USB 3.0 and 1.1 compatible
  • Sustained sampling speeds up to 500kHz
  • 12 or 16-bit resolution A/D converter
  • Flexible, software configured functionality
  • 64 single-ended or 32 differential analog inputs
  • 8 input ranges, 4 unipolar and 4 bipolar, per 4-channel programmable
  • Autocalibration and oversampling for real-time accurate data
  • A/D starts via software, timer, or external trigger
  • 2 16-bit analog outputs available
  • 16 high-current digital I/O lines
  • 16-bit programmable counter/timer
  • I/O connections made via DB37 and DB25 connectors
  • Alternate micro-fit embedded USB header connector
  • USB/104 form-factor for OEM embedded applications
  • PC/104 module size (3.550″ by 3.775″) and mounting compatibility
  • All required power drawn from USB port, no external power adapter required
  • Type B USB connector features industrial strength and high-retention design
  • Designed, made, supported, and manufactured in the USA


  • Industrial operating temperature (-40°C to + 85°C)
  • Reference junction sensor with two 37-pin terminal blocks
  • RoHS compliant version available. Please contact us for ordering information
  • Enclosed version, DAQ-PACK-M (DPK) features mounting compatibility, and can be found on the DPK-AIO16-64MA page
  • Support for Wind River VxWorks (call for ordering information)
Last updated on March 26, 2024, 1:53 pm


In Stock


The USB-AIO M Series is a highly integrated multifunction data acquisition and control system. The system offers an ideal solution for adding portable, easy-to-install high-speed analog and digital I/O capabilities to any PC or embedded system with a USB port. These units are USB 2.0 high-speed devices, offering the highest speed available on the USB 2.0 bus. It is available with 12 or 16-bit analog to digital converters with speeds capable of up to 500kHz (divided equally by the total number of channels configured for use) for its 64 single-ended or 32 differential analog inputs. Groups of four channels at a time can be independently software configured to accept 8 different input ranges. A unique, real-time internal calibration system allows the unit to continually compensate for offset/gain errors giving a more accurate reading. Additional features include two 16-bit analog outputs, 16 high-current digital I/O lines, and a programmable 16-bit counter. The counter can be configured in a variety of modes and has the ability to use external signals to trigger and control the scanning of its analog inputs. The unit is plug-and-play allowing a quick connection whenever you need additional I/O on the convenience of a USB port.

The small, compact, multifunction I/O USB-AIO M Series units provide the user with everything needed to start acquiring, measuring, analyzing, and monitoring in a variety of applications. These data acquisition and control devices can be used in many current real-world applications such as precision measurement, analysis, monitoring, and control in countless embedded applications.

These units are designed to be used in rugged industrial environments but are small enough to fit nicely onto any desk or testing station. The boards are PC/104 sized (3.550 x 3.775 inches, 90mm x 96mm) and have the same mounting holes for added flexibility. A DIN rail mounting provision and industrial operating temperature is available for installation in industrial environments.

The boards feature eight standard analog voltage input ranges (independently configured) and include a data sample buffer.

Analog to digital conversion starts or “A/D starts” are issued one of three ways: Software Start, Timer Start, or External Trigger Start. A/D starts are software configured to be either rising or falling edge. Additionally, A/D starts are software configured to be Single Channel or Scan. Single Channel samples data once from the next consecutive channel within the enabled set. A Scan samples data from all channels within the set at the fastest possible rate.

A fully programmable 8254 16-bit counter is provided with a maximum input frequency of 10MHz. The clock, gate (inputs) and output can be accessed externally for extended functionality. The counter can be configured in a variety of modes and has the ability to use external signals for its inputs.


Advanced calibration models feature a unique real-time internal autocalibration system that allows the board to compensate for offset/gain errors, giving a more accurate reading. To minimize noise, the board offers a technique called oversampling. Additionally, each channel contains its own analog ground pin on the I/O connector which is helpful in reducing noise from external signal sources. The channel-by-channel programmable gain feature enables measurement of an assortment of large and small signals in one scan—all under software control at up to 500kHz. The board’s data buffer and ability to trigger the A/D in real time assures synchronized sampling that is unaffected by other computer operations—an essential requirement for signal, vibration and transient analysis where high data rates must be sustained for short periods of time. More information regarding calibration can be found in the product manual.

Each board shipped from ACCES is factory calibrated as part of the production process using a high-quality 7 digit digital voltmeter (DVM) and an extremely stable voltage reference.


The OEM (boards only) version is perfect for a variety of embedded applications. What makes the OEM option unique is that the PCB size and pre-drilled mounting holes match the PC/104 form factor (without the bus connections). This ensures easy installation using standard standoffs inside most enclosures or systems. The board can be added to any PC/104-based stack by connecting it to a USB port usually included on-board with embedded CPU form factors such as EBX, EPIC, PC/104, and COM Express. This is especially important since many newer CPU chipsets do not support ISA and have plenty of USB ports. The USB-AIO M Series boards can also be installed using standoffs inside other enclosures or systems. For embedded OEM type applications, an additional micro-fit USB input header is provided in parallel with the type B connector.

High Retention USB Connector

The ever-growing presence of USB in the industrial/military marketplace has driven the need for USB connections to be reliable, dependable, and unfailing. Gone are the days of loose USB connections. A type B USB connector is used on all ACCES USB products which features a high retention design that complies with the class 1, Div II minimum withdrawal requirement of over 3 pounds of force (15 Newtons). This connector has an orange color-coded insulator to quickly differentiate it from standard USB connectors. Using these USB connectors increases reliability in your system and ensures a tight connection. For embedded OEM type applications, an additional micro-fit USB input header is provided.

Optional Enclosure

The USB-AIO M Series is available packaged in a small, rugged, industrial gold-zinc plated steel enclosure with an anti-skid bottom. The enclosure is useful in industrial environments and protects the boards from potential environmental hazards. The unit enclosure is 4.680″ x 3.660″ x 2.820″ and features a DIN rail and panel mounting provision. Please visit the DAQ-PACK M Series webpage to order the enclosed unit.


  • Equipment monitoring
  • Environmental measurements
  • Embedded OEM
  • Education/Laboratory
  • Portable
  • Industrial Automation
  • Precision Measurement
  • Analysis, Monitoring, and Control


Available accessories include a wide variety of cables and screw terminal boards for quick and easy-to-use, out of the box, connectivity. Also, a DIN rail mounting provision and gold-zinc mounting plate is available for panel mounting.


Data Sheets



Drivers and Downloads

Full list of available Downloads: Software Packages, Drivers, Manuals, and other documents

Information about our Free Software packages:

ACCES is proud to provide a full suite of software support with every Data Acquisition product. We are committed to supporting the most popular operating systems and platforms for our customers. Currently we are actively supporting XP -> 10, both 32 & 64 bit, including “Server 2008,” “Embedded,” and “Compact” flavors for all plug-and-play products including PCI, PCI Express, USB, and more. Many products continue to ship with support for additional operating systems such as DOS, Windows 95, 98, Me, NT4, and 2000.


Among the software we deliver with our products are sample programs in a wide variety of programming languages. These samples are used to demonstrate the software interfaces to our products — and many can be used as-is in your production environments, or to test functionality of the devices out-of-the-box. We’re currently actively supporting sample programs in Microsoft Visual C#, Visual Basic, Delphi, and Visual C/C++, with many devices including samples in Borland C/C++ 3.1 for DOS. Additionally we provide National Instruments LabVIEW compatible DLLs and many demonstration VIs for our devices.


Drivers for various operating systems are also provided, including active support for Windows XP -> 10 — all in both 32-bit and 64-bit flavors, and including consumer, server, and embedded varieties — as well as the 2.6 and newer Linux kernels and recent OSX / macOS versions. Many products continue to ship with driver support for Windows 95, 98, Me, NT4, and Windows 2000, but support for these operating systems is considered deprecated.

Setup Programs and Utilites

Our Data Acquisition devices also include a graphical setup utility that walks you through the process of configuring any option jumpers or switches on the device, as well as explaining a little about the various connectors present.

Many devices also include utility programs – little tools to make your use of the device easier, such as EWriter, a program that allows you to read and write data in the user-accessible EEPROM locations on all our USB data acquisitition products; or WinRISC, a “Really Incredibly Simple Communications” terminal program that lets you get started instantly with serial devices.

“Register Level” Documentation

Besides all this software in all these languages and operating systems ACCES has a policy of open and transparent development: none of our lowest-level “register” interfaces are hidden from you — we document every register in every bus card, every command in every serial board, and every usb control transfer in every USB Data Acquisition board. These lowest-level interfaces allow you to develop for our products in ANY operating system or language, regardless of our actively supporting it or having a driver for it. We have customers actively developing in ADA, Android, Python, Java, MATLAB, Solaris, and more, just by referring to our complete low-level interface documentation! And we provide the full source code to all of our drivers, regardless of operating system, to give you an even bigger head start in your own development tasks.

No Fees or Royalties

All of this software is provided at no additional charge, and is licensed under any of a variety of flexible — and royalty free — options. Check out our software license explanation if you’d like more information.

Custom Software

ACCES also offers Custom Software Services for our products. Our prices are unbelievably low, often as inexpensive as free! If you need something tweaked to support your needs, or an entire enterprise application developed from scratch, it is definitely worth your time to inquire with us, first.

Further information about available ACCES Software:

Redistributing Windows Drivers
A list of ACCES drivers and the files that compose them under different versions of Windows, so you can easily redistribute ACCES cards and drivers.

Analog Inputs

ADC Type		Successive approximation
Resolution		12 or 16-bit
Sampling rate
 "16-64MA" version	500Ksamples/sec (maximum aggregate)
 "16-64ME" version	250Ksamples/sec (maximum aggregate)
 "12-64MA" version	500Ksamples/sec (maximum aggregate)
 "12-64M" version	250Ksamples/sec (maximum aggregate)
 "12-64ME"version	100Ksamples/sec (maximum aggregate)
Number of channels	64 single-ended or 32 differential (software selectable)
Unipolar ranges		0-1V, 0-2V, 0-5V, 0-10V (software selectable)
Bipolar ranges		±1V, ±2V, ±5V, ±10V (software selectable)
Calibration Hardware
 "16-64MA" version	Two on-board references + calibrated real-time output
 "16-64ME" version	Two on-board references
 "12-64MA" version	Two on-board references + calibrated real-time output
 "12-64M" version	Two on-board references
 "12-64ME"version	NONE
System Calibration	Program provided to calibrate entire system
Accuracy		Uncalibrated	0.094% Full-Scale (FS)
			Calibrated(*)	0.0015% FS
Int Nonlinearity Error	0.0046% FS
No Missing Codes	15 bits
Input impedance		1MΩ
A/D Start Sources	Software Start, Timer Start, and External Start Trigger
			(rising or falling edge; software selectable)
A/D Start Enable	Externally supplied (pulled-up; active-high)
A/D Start Types		Single Channel or Scan (software selectable)
Channel Oversampling	0-255 consecutive samples/channel (software selectable)
Overvoltage protection	-40 to +55V
Crosstalk		-60dB @ 500KHz
(*) To achieve best accuracy, one must calibrate to their own standard

Analog Outputs

Number/Type		2/single-ended
Resolution		16-bit
Unipolar Ranges		0-5V*, 0-10V*
Bipolar Ranges		±5V*, ±10V*
Conversion Rate		4kHz per channel
Settling Time		4us typ, 7us max; 1/4 to 3/4 scale to ±2LSBs
Output Current		±25mA per channel

* Factory Options

Digital I/O

Lines			16, programmable as inputs or outputs in groups of 8 (pulled-up)
Input voltage		Logic low:	0V(min) to 0.8V(max)
			Logic high:	2V(min) to 5V(max)
Input current		±20µA (max)
Output voltage		Logic low:	0V(min) to 0.55V(max)
			Logic high:	2V(min) to 5V(max)
Output current		Logic low:	64mA(max) sink
			Logic high:	32mA(max) source


Type			82C54 programmable interval counter
Available Counters	CTR0 (CTR1/CTR2 dedicated to A/D starts)
Input Frequency 	10MHz (max) Int. or ext. supplied (sw select; pulled-up)
Counter size		16-bit
Clock 			Internal 10MHz or Externally supplied
			(software selectable; pulled-up)
Clock Period		100ns (min)
Clock Pulse Width High	30ns (min)
Clock Pulse Width Low	40ns (min)
Gate			Externally supplied (pulled-up; active-high)
Output			External (pulled-up)
Voltage/Current		Same as Digital I/O


Operating Temperature	0° to +70°C, optional -40° to +85°C
Storage Temperature	-40° to +105°C
Humidity		5% to 90% RH, without condensation
Enclosure Dimensions	4.680" x 3.660" x 2.820"
Power required		+5V at 320mA typical*

*USB 2.0 spec defines a device in terms of a unit load. A unit load is defined to be 100mA. Devices drawing an absolute maximum of one unit load is considered to be low-powered and devices drawing an absolute maximum of five unit loads is considered to be high-powered. Because this spec is not strictly adhered to, it is best to verify the USB port’s power capabilities before operation. This card, according to the USB 2.0 spec, is a high powered device. An optional external power supply can be ordered if the USB port cannot support high powered devices.

If using more than a total of 500mA, use optional 5 VDC external power supply and remove VUSB jumper and place jumper on VEXT. Then plug in external power before plugging into USB port . This option will give you a total of 1000mA available.

Included with your board

The following components are included with your shipment:

  • 6’ USB cable
  • Software Master CD (PDF user manual installed with product package)
  • Printed USB I/O Quick-Start Guide

All M Series USB-AIO OEM boards include either 64 single-ended or 32 differential inputs on all channels, 16 5VTTL DIO lines, unipolar and bipolar ranges software selectable, onboard ADC FIFOs, and are available in extended temperature versions. All AIO units include two 16-bit DACs with your choice of 0-10V (-10U), ±10V (-10B), 0-5V (-5U), or ±5V (-5B) output range.

ModelDescriptionPrice (USD)

64-Channel, 16-Bit, 500kHz Analog Input USB OEM Stack


64-Channel, 16-Bit, 250kHz Analog Input with Two 16-bit Analog Output USB OEM Stack


64-Channel, 16-Bit, 250kHz Analog Input USB OEM Stack


64-Channel, 16-Bit, 500kHz Analog Input with Two 16-bit Analog Output USB OEM Stack


64-Channel, 12-Bit, 500kHz Analog Input with Two 16-bit Analog Output USB OEM Stack


64-Channel, 12-Bit, 100kHz Analog Input with Two 16-bit Analog Output USB OEM Stack


64-Channel, 12-Bit, 250kHz Analog Input with Two 16-bit Analog Output USB OEM Stack


64-Channel, 12-Bit, 100kHz Analog Input USB OEM Stack


USB 64-Channel, 16-Bit, 500kHz Analog Input with Two 16-bit Analog Output, OEM Stack


64-Channel, 12-Bit, 250kHz Analog Input USB OEM Stack

For the DB37 connectors
ADAP37M-MINI Screw terminal adaptor for use with 37-pin female connector $40
CAB37MF-18 Ribbon cable, male to female 37-pin connectors, 18″ $29
CAB37MF-xx As above except “xx” equals length in inches (add $2 per Ft over 18″)
STB-37 DIN-rail mountable screw terminal board for 37-pin connector $39
J37Mxx Kit Custom connectivity component kit for 37-pin D-Sub connector
For the DB25 connector
CAB25MF-18 Ribbon cable, male to female 25-pin connectors, 18″ $29
ADAP25M Screw terminal adaptor for use with 25-pin female connector $50
STB-25 DIN-rail mountable screw terminal board for 25-pin connector $44
CAB25MF-xx As above except “xx” equals length in inches (add $2 per Ft over 18″)
J25Mxx Kit Custom connectivity component kit for 25-pin D-Sub connectorxx
Hardware and Power
DIN-SNAP One foot length SNAP-TRACK with four clips for mounting up to two STB-xx screw terminal boards $20
DIN-SNAP-6 Six inch length SNAP-TRACK with two clips for mounting one STB-xx screw terminal board $15
DPK-DIN-CLIP DIN rail mounting provision $XX
DPK-MOUNT Panel mounting provision $XX
PWR-ACDC-5V +5V DC external power and regulated AC/DC adapter $25
Options (call for pricing)
-T Industrial operating temperature (-40°C to +85°C)
-MTC Thermocouple Reference Junction Sensor installed with two DB37 terminal blocks (ADAP37M-MINI)